Surgical Sealants & Adhesives Market By Product Type (Natural Sealants & Adhesives {Fibrin-Based Sealants, Collagen-Based Sealants, Gelatin-Based Sealants, Albumin-Based Sealants, Polysaccharide-Based Sealants), Synthetic & Semi-Synthetic Sealants & Adhesives{Polyethylene Glycol (PEG)-Based Adhesives, Cyanoacrylate-Based Adhesives, Polyurethane-Based Adhesives, Hydrogel-Based Adhesives, Acrylic-Based Adhesives}), By Application (Tissue Sealing, Hemostasis, Tissue Engineering, Wound Closure, Dural Sealing, Ophthalmic Surgery, Drug Delivery, Others), By Origin (Natural, Synthetic, Hybrid), By End User (Hospitals, Ambulatory Surgical Centers, Clinics, Specialty Surgical Centers, Academic & Research Institutes), Global Market Size, Segmental analysis, Regional Overview, Company share analysis, Leading Company Profiles and Market Forecast, 2025 – 2035

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Industry Outlook

The Surgical Sealants & Adhesives Market accounted for USD 2.91 Billion in 2024 and USD 3.25 Billion in 2025 and is expected to reach USD 9.86 Billion by 2035, growing at a CAGR of around 11.73% between 2025 and 2035. Surgical sealants and adhesives are designed to close open wounds, unite tissues, and stop bleeding at the site of surgery. They work alongside sutures and staples, giving doctors a quicker option while having the potential to decrease the chances of infections or issues. Many surgeries in cardiovascular, orthopedic, neurological, and general medicine depend on these products because they permanently seal tissues and speed up healing. Both the demand and sales for surgical sealants and adhesives are rising, due to more surgical procedures, surgeons preferring less invasive methods, and the introduction of new bio-compatible materials. Since hospitals and surgical centers work to increase patient well-being and cut down on surgery time, the world continues to need dependable and innovative sealing solutions.

Industry Experts Opinion

“Fibrin sealants are valuable adjuncts in surgical practice, offering effective hemostasis and tissue adhesion, which can reduce operative time and improve patient outcomes.”

• Dr. William D. Spotnitz – Cardiothoracic Surgeon and Director, Surgical Therapeutic Advancement Center, University of Virginia Health System.

Report Scope:

Market Dynamics

The rising number of surgeries worldwide is increasing the demand for surgical sealants and adhesives to reduce bleeding and speed up healing.

Increased surgical volume worldwide has greatly boosted demand for the Surgical Sealants & Adhesives Market. As more people need surgery because of ageing, more chronic illnesses, or easier access to healthcare, demand is increasing for products that reduce surgery-related problems both in and after the procedure. Doctors use sealants and adhesives in surgery to stop bleeding quickly, close wound areas securely, and reduce escaping liquid. Products like these give patients a better option than using sutures and staples because they are generally quicker, safer, and more trustworthy. More surgeons use these methods as they can cut operating time, lower infections, and quicken a patient’s recovery. Growing trust in sealants and adhesives leads to their more common use in any type of surgical procedure.

The demand is also present in many various specialties. Adhesives and sealants now assist surgeons in operations for cardiovascular, orthopaedic, neurological, and gastrointestinal diseases. Because they help fix tissue in sensitive and hard-to-reach regions, these staples are very useful. Hospitals and surgical centres are making greater investments in advanced sealing solutions as they aim to improve how efficiently they work and better care for patients. Because minimally invasive surgery is gaining popularity around the world, companies need products that help seal wounds promptly and with minimal harm. Since bio-compatible and synthetic adhesives are finding wider use in surgery, improvements in sealant technologies are keeping the surgical sector well-poised for further growth.

The growing popularity of minimally invasive surgeries needs better closure materials, which boosts the use of sealants and adhesives.

The increase in MIS procedures is strongly encouraging demand for surgical sealants and adhesives. Compared to large open procedures, they have less damage, require fewer cuts, and help the patient get well soon. Yet, because it is challenging to close areas precisely during MIS, the technique requires speed and careful handling. Such delicate procedures often do not benefit from applying traditional sutures or staples, which may be hard to secure properly and might not seal the section well in cramped surgical areas. Sealants and adhesives are easy to apply, attach very well to tissues, and provide increased sealing ability. Because they can deal with irregular surfaces, robots are crucial for use in current MIS procedures.

As surgeons increasingly opt for laparoscopic, endoscopic, and robotic procedures, the use of new wound-closing methods is also growing. They help avoid leaks in the surgical site, excessive bleeding, and infection, which are common after MIS. The fact that these adhesives help clot blood and seal tissues safely helps wounds heal faster. Moving towards same-day surgery means that products used to close wounds must minimize the risk of complications. More people choosing minimally invasive treatments and regular improvements in biocompatible and synthetic adhesives are projected to boost growth in the Surgical Sealants & Adhesives Market. Because of this, these products are now necessary for surgeons in the growing field.

Surgical sealants and adhesives are often expensive, making them less affordable for smaller hospitals and clinics.

An important barrier to market growth is that surgical sealants and adhesives are too expensive for smaller hospitals and clinics. These products use sophisticated biomaterials and technology, so making them is far more costly. As a result, health products for patients are now more expensive, making them unavailable to health providers in locations with limited resources. Many rural and financially strained medical facilities might have a hard time buying these products because of the costs. That is why they keep depending on stitches and staples for closing wounds, as they are low-cost but do not always provide as many benefits as some advanced alternatives.

Things are made far worse for developing countries since managing costs and securing funding are major struggles for their healthcare systems. Because there is limited funding, hospitals must treat essential equipment and treatments as more urgent and place surgical sealants and adhesives further down the list. Besides, having to pay more for advanced surgical closure materials is often discouraged by insurance companies or state healthcare programs. Budget problems in public hospitals in advanced countries may keep them from using these latest medical technologies regularly. For this reason, while the benefits of surgical sealants and adhesives are clear, their price limits their use by many. To unlock the full growth potential of this market, we must improve costs in manufacturing and come up with new ways to reward health providers.

Developing countries are building more hospitals and increasing surgeries, which creates new markets for these products.

The surgical sealants and adhesives market is set to grow significantly because of the rapid growth of healthcare structures in developing countries. Healthcare services in Asia, Africa, and Latin America are being supported with new hospitals, updated medical systems, and improved surgical options for patients. With more sports being performed and surgical care offered, there is a greater need for advanced products used in closure, for example, sealants and adhesives. The use of these products helps surgeons achieve better surgery results by lessening bleeding, putting wounds on the mend quickly, and decreasing the chance of infections. Since surgery is becoming more common in these locations, the market for these solutions is expected to grow gradually. Both public and private organizations in developing nations are making it easier for healthcare technology companies to be present and prosper, as they support affordable healthcare.

International medical device companies are getting partners in these emerging countries through local manufacturing companies and distributors. More healthcare professionals are using surgical sealants and adhesives due to training courses explaining their uses. As people find out more about these products and prices reduce, hospitals are more likely to include them in their standard surgeries. As countries improve their surgical services, placing more focus on quality and safety, developing regions begin to offer businesses many opportunities. As a result, working in these rising markets opens up new opportunities for manufacturers to reach a bigger audience and raise their profits.

Companies can grow by making different types of sealants for specific surgeries like heart, lung, or brain procedures.

One of the promising opportunities in the Surgical Sealants & Adhesives Market lies in the development of specialized products tailored for specific surgical procedures, such as cardiovascular, pulmonary, or neurological surgeries. Each type of surgery has unique needs, for example, heart surgeries require sealants that can withstand high blood pressure, while brain surgeries demand products that are gentle on sensitive tissues and do not swell. By creating sealants designed for these specific medical applications, companies can offer more effective solutions that enhance surgical outcomes. This level of customization not only improves patient safety but also boosts surgeon confidence in the product's performance. As a result, such specialized sealants can command premium pricing and establish brand loyalty among healthcare providers.

Hospitals and surgeons are increasingly seeking precision tools and materials that reduce complications and speed up recovery. Offering sealants specifically designed for different organs or types of tissue supports this trend toward personalized medical solutions. Companies investing in research and innovation to create these advanced sealants can gain a competitive edge and differentiate themselves in the market. This strategy also opens the door to new patents, partnerships with leading hospitals, and opportunities in training and education. Regulatory bodies may favour specialized products that demonstrate enhanced safety and efficacy, leading to smoother approval processes. In this way, the move toward procedure-specific surgical sealants is not just a technical advancement but a strategic pathway for companies to expand their reach, strengthen their portfolio, and drive long-term growth in the global surgical sealants and adhesives market.

Segment Analysis

Based on product type, the Surgical Sealants & Adhesives Market is segmented into Natural Sealants & Adhesives and Synthetic & Semi-Synthetic Sealants & Adhesives. The most popular are Natural Sealants & Adhesives because they are safe, easy to use, and don’t usually cause an immune response. These products are highly regarded in cardiovascular, orthopaedic, and general surgeries where the body’s healing process is important. The use of these meds is growing because they bring about strong medical results and higher security for patients.

Based on application, the Surgical Sealants & Adhesives Market is segmented into Tissue Sealing, Hemostasis, Tissue Engineering, Wound Closure, Dural Sealing, Ophthalmic Surgery, Drug Delivery, and Others. Tissue Sealing is currently the biggest part of the market. This success is mostly due to its help in avoiding surgical risks, stopping leaks, and making recovery faster. As more and more surgeries become less invasive and more complicated, the need for effective sealing products has gone up. This area is using technological advances and a surge in the global need for quick and trustworthy sealing options in hospitals and surgical centers.

Regional Analysis

The North American surgical sealants and adhesives market is highly advanced, driven by well-established healthcare infrastructure and a high volume of surgical procedures. The area makes good use of research and development, which has resulted in the quick adoption of top sealing technology. With well-known medical device manufacturers and government approval for products, the industry offers better quality and greater availability. Doctors in the USA and Canada are increasingly selecting minimally invasive procedures, which is driving the need for devices. Additionally, increasing clinic costs and patients being informed about faster recovery have helped hospitals decide to use updated sealant materials. Teaming up for clinical trials by hospitals and medical firms is playing a role in the development of the market.

The Asia Pacific surgical sealants and adhesives market is growing rapidly due to improvements in healthcare infrastructure and rising surgical volumes across emerging economies. Due to rising numbers of chronic health conditions and more senior patients, China, India, Japan, and South Korea are now using more advanced surgical instruments. Budgets from governments to increase healthcare are allowing hospitals to include cutting-edge products such as surgical adhesives. Because local manufacturing and distribution are becoming more common, products are now more easily reached in urban and semi-urban areas. Because the cost of sealants is an obstacle in some regions, knowledge about after-surgery care and new minimally invasive methods is slowly helping more people to adopt them. More patients coming for medical tourism in the area are looking for superior and efficient surgical solutions.

Competitive Landscape

Multiple global and regional leading companies seek to innovate further and expand their collections of surgical sealants and adhesives. Authors indicate that Baxter International Inc., Becton, Dickinson and Company, Ethicon Inc. (a Johnson & Johnson branch), and CryoLife Inc. are investing in research and development to design innovative sealants that attach better, do not harm the body, and are simpler to use. To improve their share in the global market, many companies are relying on forming alliances, buying out competitors, and introducing new offerings. More competition and better access to products are appearing in emerging markets because newer manufacturers and regional players are offering affordable solutions.

Surgical Sealants & Adhesives Market, Company Shares Analysis, 2024

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Recent Developments:

• In November 2023, the hemostatic sealing patch Ethizia was released by Ethicon, a unit of Johnson & Johnson’s MedTech segment.
• In November 2023, Pramand LLC began selling the CraniSeal Dural Sealant System to U.S. customers. Today, cranial surgeons make use of this method.

Report Coverage:

By Product Type

• Natural Sealants & Adhesives
  • Fibrin-Based Sealants
  • Collagen-Based Sealants
  • Gelatin-Based Sealants
  • Albumin-Based Sealants
  • Polysaccharide-Based Sealants
• Synthetic & Semi-Synthetic Sealants & Adhesives
  • Polyethylene Glycol (PEG)-Based Adhesives
  • Cyanoacrylate-Based Adhesives
  • Polyurethane-Based Adhesives
  • Hydrogel-Based Adhesives
  • Acrylic-Based Adhesives

By Application

• Tissue Sealing
• Hemostasis
• Tissue Engineering
• Wound Closure
• Dural Sealing
• Ophthalmic Surgery
• Drug Delivery
• Others

By Origin

• Natural
• Synthetic
• Hybrid

By End User

• Hospitals
• Ambulatory Surgical Centers
• Clinics
• Specialty Surgical Centers
• Academic & Research Institutes

By Region

North America

• U.S.
• Canada

Europe

• U.K.
• France
• Germany
• Italy
• Spain
• Rest of Europe

Asia Pacific

• China
• Japan
• India
• Australia
• South Korea
• Singapore
• Rest of Asia Pacific

Latin America

• Brazil
• Argentina
• Mexico
• Rest of Latin America

Middle East & Africa

• GCC Countries
• South Africa
• Rest of the Middle East & Africa

List of Companies:

• Ethicon Inc.
• Baxter International Inc.
• B. Braun Melsungen AG
• Medtronic plc
• CryoLife Inc.
• C.R. Bard Inc.
• Integra LifeSciences Holdings Corporation
• Cardinal Health Inc.
• Adhezion Biomedical LLC
• Cohera Medical Inc.
• Tissuemed Ltd.
• Ocular Therapeutix Inc.
• Vivostat A/S
• Advanced Medical Solutions Group plc
• Sanofi S.A.

Frequently Asked Questions (FAQs)