Topical Cyanoacrylates Market By Product Type (Joint Reconstruction Devices, Trauma Devices, Spinal Devices, Arthroscopy Devices, Orthobiologics, Orthopedic Braces & Supports, Others), By Application (Hip Disorders, Knee Disorders, Spine Disorders, Shoulder & Elbow Disorders, Foot & Ankle Disorders, Hand & Wrist Disorders, Others), By Technology (Conventional Orthopedic Devices, Minimally Invasive Surgical Devices, Robotic-assisted Orthopedic Devices, 3D Printed & Patient-specific Implants, Smart Orthopedic Implants, Others), By Biomaterial (Metallic, Polymer-based, Ceramic-based, Biological Materials, Composite Materials), By Procedure Type (Joint Replacement Surgery, Trauma Fixation Surgery, Spinal Surgery, Arthroscopy, Orthopedic Oncology Surgery, Others), By End User (Hospitals, Orthopedic Clinics, Ambulatory Surgical Centers, Rehabilitation Centers, Academic & Research Institutes), Global Market Size, Segmental analysis, Regional Overview, Company share analysis, Leading Company Profiles And Market Forecast, 2025 – 2035

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What trends will shape Topical Cyanoacrylates Market in the coming years?

The Topical Cyanoacrylates Market accounted for USD 98.24 Million in 2024 and USD 103.72 Million in 2025 is expected to reach USD 178.52 Million by 2035, growing at a CAGR of around 5.58% between 2025 and 2035. The topical cyanoacrylates market is the industry that deals with the medical-grade cyanoacrylate adhesives in skin closure and wound care. They are fast-action adhesives that are usually applied instead of sutures or staples during surgery or emergency situations and with minor wound cases. They develop a tough protective coating around the wounds and facilitate healing with a low chance of infection. Rising demand for non-invasive procedures, the growing number of surgical volumes, and high wound care technologies are the drivers of the market. The most important end-users are hospitals, clinics, and ambulatory surgical centres.

What do industry experts say about the Topical Cyanoacrylates market trends?

"Topical cyanoacrylates have become an essential tool in wound closure, providing strong tissue adhesion, reduced infection risk, and faster recovery compared to traditional sutures."

• Dr. Peter R. DiMaio, Associate Professor of Surgery, Boston University School of Medicine

"In trauma and orthopedic settings, cyanoacrylate adhesives are increasingly used as adjuncts to sutures or staples, improving cosmetic outcomes and minimizing patient discomfort."

• Dr. Brett D. Crist, Professor of Orthopaedic Surgery, University of Missouri; Director, Orthopaedic Trauma Service

Which segments and geographies does the report analyze?

What are the key drivers and challenges shaping the Topical Cyanoacrylates market?

Is rising demand for wound-closure contributing to global market growth?

The topical cyanoacrylates business is growing due to the increased demand for wound-closure products. Cyanoacrylates are used as substitutes for the traditional sutures, being faster to use and with lower chances of infection. The World Health Organisation (WHO) notes that more than 310 million surgeries were conducted worldwide in 2018, and the figures are expected to increase as the accessibility of healthcare improves across the world. There is a drastic increase in chronic wounds according to the Centers for Disease Control and Prevention (CDC), particularly in aged populations and diabetic patients, which impacts almost a quarter of U.S. adults, up to 11.3%.

The trends put more pressure on the necessity to develop more sophisticated wound closure techniques that will ensure faster recovery and fewer complications. Schools emphasise the fact that cyanoacrylate adhesives are beneficial because of the lesser procedure time, as well as enhanced patient comfort, and they are becoming more popular in operating and emergency rooms. The net effect of these forces, and is the growing use and market development of topical cyanoacrylates.

Does increased surgical procedures influence adoption of cyanoacrylate adhesives?

The use of topical cyanoacrylate adhesives has been greatly motivated by the increase in the number of surgical procedures in the global world. The Centers for Disease Control and Prevention (CDC) notes that more than 50 million surgeries are performed in the United States alone each year, which results in the increased demand for effective wound closure procedures. The benefits of cyanoacrylate adhesives include that they take a shorter time to apply, have a lower rate of infection, and are more comfortable for the patient than conventional sutures.

Research funded by groups such as the National Institutes of Health (NIH) proved that these adhesives may inhibit surgical site infections by almost half in some surgeries. Wounds heal at a higher rate, reducing the total time the surgical procedures consume, which is vital with high-volume surgeries. This clinical and operational advantage has contributed to the further integration of cyanoacrylates in surgical practice, making them the choice of many healthcare professionals.

Are pricing pressures affecting profit margins for manufacturers globally?

The topical cyanoacrylate market exhibits high pressure in prices that are squeezing profit margins of manufacturers across the globe. Whether due to inflationary trends that the U.S. Bureau of Labour Statistics (BLS) has been reporting on or not, price increases in raw materials have been rising, with producer prices of chemicals rising approximately 6% over the last year, a direct increase in the cost of production.

Statistics provided by the International Monetary Fund (IMF) indicate the existence of continuous global inflationary pressures, which restrain the capacity of the manufacturers to transfer the rising prices to consumers without jeopardising the reduction of sales volumes. This pressure compels most businesses to incur increased costs, which causes narrow profit margins.

The volatile supply chain expenses (such as transportation and energy, all of which the U.S. Energy Information Administration (EIA) indicated have risen in recent years by almost 10 per cent) contribute to the cost pressures in general. In turn, producers are forced to find a compromise between competitive pricing and profitability, which makes the topical cyanoacrylates industry a challenging market that limits the growth potential.

Will innovation in formulation lead to extended usage across applications?

Formulational innovation is set to greatly increase the range of applications of topical cyanoacrylates. According to research by the U.S. Food and Drug Administration (FDA) and articles published by the National Institutes of Health (NIH), recent developments in cyanoacrylate chemistry, including increased biocompatibility, shortened curing, and increased flexibility, have opened up a wide range of applications beyond the traditional wound closure scenario, to such uses as minimally invasive surgeries, dental treatments, and even delivery systems. As an example, less toxic and more elastic formulations can be used on delicate tissues, and the clinical application of the formulation can be expanded.

The medical device reports provided by the FDA indicate that cyanoacrylate-based wound closure items approved by the agency have steadily increased in the last decade, attributable to increased confidence in innovative compounds. Moreover, research on biomaterials conducted in universities, including Johns Hopkins and MIT, highlights the integration of nanotechnology with cyanoacrylates to enhance adhesive properties and controlled degradation, leading to new uses in tissue engineering, medical device coatings, and more. The combination of these formulation innovations indicates a movement to broader applications of topical cyanoacrylates in multiple medical and industrial applications.

Can emerging markets accelerate adoption of advanced wound closure systems?

The potential of emerging markets to expedite the use of advanced wound closure systems, such as topical cyanoacrylates, is substantial because of the growing health care expenditure and rising illnesses. The World Health Organisation (WHO) indicates that more than 80% of the worldwide diabetes population is in low- and middle-income countries, among other factors that contribute to the need for using more sophisticated closure methods.

According to the World Bank statistics, the level of healthcare spending in countries like India and Brazil is gradually rising, making access to modern medical technologies easier. Such institutions as the All India Institute of Medical Sciences (AIIMS) emphasise the fact that cyanoacrylate adhesives can decrease the number of cases of infection and accelerate the healing of wounds better than conventional sutures.

Advanced wound care products are also being provided by government health programmes in the emerging markets, and this is an indication of a change in the trend towards the modernisation of the healthcare infrastructure. This set of increased demand as a result of the rising occurrence of chronic illnesses, increased healthcare budgets, and supportive policies makes emerging markets crucial in enhancing the faster adoption of the latest wound closure technologies.

What are the key market segments in the Topical Cyanoacrylates industry?

Based on the product type, the Topical Cyanoacrylates Market has been classified into Joint Reconstruction Devices, Trauma Devices, Spinal Devices, Arthroscopy Devices, Orthobiologics, Orthopedic Braces & Supports, and Others. Trauma devices become the most outstanding segment in the topical cyanoacrylates market.

The main reason is that topical cyanoacrylates are popular as tissue adhesives in trauma care to close wounds and provide a faster and non-invasive option to conventional sutures and staples. They are very popular in traumatology because of their capability to minimise the risk of infection and shorten the time of healing. Also, a rise in the number of accidents and emergency care conditions contributes to increasing demand in this segment, and the use of topical cyanoacrylates in trauma devices becomes the primary application field.

Based on the application, the Topical Cyanoacrylates Market has been classified into Hip Disorders, Knee Disorders, Spine Disorders, Shoulder & Elbow Disorders, Foot & Ankle Disorders, Hand & Wrist Disorders, and Others. The Knee Disorders segment is the most important application in the Topical Cyanoacrylates Market. This is because knee injuries and surgeries are very common and usually demand good wound-closing remedies.

Topical cyanoacrylates provide a low-risk, faster, and less invasive way to seal all surgical wounds and minor cuts, which ensures faster healing and reduces the risk of infection. The increase in the rate of athletic injuries and degenerative knee diseases also augments the necessity of these adhesives in the treatment of knees, and this segment is predominant in the marketplace.

Which regions are leading the Topical Cyanoacrylates market, and why?

The North American topical cyanoacrylates market is leading since there is an interplay of well-established healthcare systems, high rates of wound care product awareness, and a national investment in medical research and innovation. The area enjoys a high concentration of large pharmaceutical and medical device manufacturing firms, which are in an ongoing effort to formulate and market more sophisticated adhesive products in surgical and non-surgical procedures. Moreover, an increase in surgical operations (cosmetic and reconstructive) has also led to the growth of the need to find efficient and fast-acting skin adhesives.

Product approvals and market entry are also fast-tracked by regulatory assistance from other agencies, such as the FDA. Furthermore, the preference for minimally invasive procedures and outpatient care by consumers also contributes to the adoption of topical cyanoacrylates in clinical practices in the United States and Canada. The increasing use of these adhesives is also caused by the growing geriatric population, which tends to have more chronic wounds and is more likely to undergo surgery. Moreover, the advanced wound care products are easily available and affordable in the region due to very strong reimbursement policies and very high healthcare spending.

The Asia Pacific topical cyanoacrylate market is rapidly developing healthcare infrastructure, a growing population, and a rising need for superior wound care technologies. Medical technologies are being heavily invested in by countries such as China, India, and Japan, a key driver in the uptake of topical adhesives in surgery and non-surgical processes.

Costs of production in the region are also lower, and the region is rich in local and international medical device firms. The increasing knowledge of the least invasive procedures and the easy access to health care in rural and urban locations also contribute to the growth of the market. Moreover, the modernisation of the public health systems by government efforts also adds to the growth in the use of cyanoacrylate-based products.

Asia Pacific is a major driver in this market due to the combination of economic development and industrial capacity, coupled with the healthcare demand. What is more, the growing rates of chronic illnesses and trauma in the area have further increased the necessity of efficient wound-closing techniques, cementing the necessity of the best topical cyanoacrylates. Increasing use of e-commerce platforms has also enabled easy access to these products by consumers and healthcare providers alike, thereby enabling increased market penetration.

What does the competitive landscape of the Topical Cyanoacrylates market look like?

The topical cyanoacrylates market is very competitive, with the leading players being the well-established medical equipment and chemical firms, which include Johnson & Johnson, 3M Company, Medline Industries, and H.B. Fuller Company. These players are continually investing in product innovation and approvals by the regulatory authorities to enhance their market shares. Businesses have been keen to enhance the biocompatibility and bonding ability of cyanoacrylate adhesives to increase their use in wound care and general surgery.

Johnson & Johnson has developed their product formulations to make them more comfortable for the patient and shorten healing time. Niche solutions that are designed to meet specific medical requirements are also becoming popular with smaller specialised companies such as Adhezion Biomedical and GluStitch Inc. There are also strategic partnerships and acquisitions that have become common, where companies seek to expand their product lines and geographical boundaries. The growing need for the least invasive surgery methods is also increasing innovation and competition in this area.

Topical Cyanoacrylates Market, Company Shares Analysis, 2024

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Which recent mergers, acquisitions, or product launches are shaping the Topical Cyanoacrylates industry?

• In August 2024, Resivant Medical received FDA 510(k) clearance for two innovative high-viscosity tissue adhesive products. These included the Cutiva™ Topical Skin Adhesive and the Cutiva PLUS™ Skin Closure System. The PLUS system featured a combination of an adhesive mesh patch and the high-viscosity adhesive.

Report Coverage:

By Product Type

• Joint Reconstruction Devices
• Trauma Devices
• Spinal Devices
• Arthroscopy Devices
• Orthobiologics
• Orthopedic Braces & Supports
• Others

By Application

• Hip Disorders
• Knee Disorders
• Spine Disorders
• Shoulder & Elbow Disorders
• Foot & Ankle Disorders
• Hand & Wrist Disorders
• Others

By Technology

• Conventional Orthopedic Devices
• Minimally Invasive Surgical Devices
• Robotic-assisted Orthopedic Devices
• 3D Printed & Patient-specific Implants
• Smart Orthopedic Implants
• Others

By Biomaterial

• Metallic
• Polymer-based
• Ceramic-based
• Biological Materials
• Composite Materials

By Procedure Type

• Joint Replacement Surgery
• Trauma Fixation Surgery
• Spinal Surgery
• Arthroscopy
• Orthopedic Oncology Surgery
• Others

By End User

• Hospitals
• Orthopedic Clinics
• Ambulatory Surgical Centers
• Rehabilitation Centers
• Academic & Research Institutes

By Region

North America

• U.S.
• Canada

Europe

• U.K.
• France
• Germany
• Italy
• Spain
• Rest of Europe

Asia Pacific

• China
• Japan
• India
• Australia
• South Korea
• Singapore
• Rest of Asia Pacific

Latin America

• Brazil
• Argentina
• Mexico
• Rest of Latin America

Middle East & Africa

• GCC Countries
• South Africa
• Rest of the Middle East & Africa

List of Companies:

• Johnson & Johnson
• 3M Company
• Medline Industries, LP
• H.B. Fuller Company
• Advanced Medical Solutions Group plc
• Medtronic plc
• B. Braun Melsungen AG
• Adhezion Biomedical, LLC
• GluStitch Inc.
• Meyer‑Haake GmbH
• Cardinal Health, Inc.
• Chemence Medical, Inc.
• Beijing Compont Medical Devices Co. Ltd.
• Cartell Chemical Co., Ltd.
• Integra LifeSciences Holdings Corporation

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